International Travel Medicine Center of Iran International Journal of Travel Medicine and Global Health 2322-1100 10 3 2022 09 01 Pulmonary Blastomycosis Masquerading as Malignancy in India; Case From a Tertiary Hospital in South India 134 136 153336 10.34172/ijtmgh.2022.24 EN Divya Rakesh Joshi Department of Infectious Diseases, Apollo Hospital, Chennai, India Senthur Nambi Department of Infectious Diseases, Apollo Hospital, Chennai, India 0000-0003-0519-8768 Rajan Santosham Department of Cardiovascular and Thoracic Surgery Apollo Hospital, Chennai, India Santosham Chest Hospital, Chennai, India 0000-0003-0350-4127 Rajiv Santosham Department of Cardiovascular and Thoracic Surgery Apollo Hospital, Chennai, India Santosham Chest Hospital, Chennai, India Journal Article 2022 04 10 <strong>Introduction: </strong>Blastomycosis is an endemic granulomatous fungal infection involving multiple organ systems predominantly the lungs. The diverse clinical spectra of the pulmonary disease encompass a subclinical infection, an acute infection mimicking a bacterial pneumonia and a chronic variant masquerading as tuberculosis or malignancy.<br /><strong>Case Presentation: </strong>Here we report a case of a middle-aged gentleman who was evaluated for a malignant pulmonary mass which was later identified as pulmonary blastomycosis. The diagnosis of blastomycosis was made through histopathology and was retrospectively corelated with a travel history to an endemic region.<br /><strong>Conclusion: </strong>The endemicity of this infection contributes to the diagnostic dilemma in the non-endemic setup. This warrants a high clinical suspicion in patients with a chronic pulmonary syndrome with a travel history to an endemic area. https://www.ijtmgh.com/article_153336_d8eca2f6fcaa894d63b4cd9dea6f4ef7.pdf