International Travel Medicine Center of Iran International Journal of Travel Medicine and Global Health 2322-1100 2 3 2014 09 01 A Closer Look to the Most Frequent Travelers’ Disease: A Systematic Update on Travelers’ Diarrhea 95 99 33292 EN Morteza Izadi Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Afshin Sadepur Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran Journal Article 2014 06 16 The present study, wants to highlight and review the most prevalent disease amongst travelers. In the current review, an updated review regarding epidemiology, involved pathogens, and a brief review of current evidence-based guidelines for prevention and treatment of this disease are provided. A distinguishing feature of the current review is the discussion of the impacts of irritable bowel syndrome, as one of the most prevalent gastrointestinal diseases, on travelers’ diarrhea pattern. Moreover, evidence-based data was the primary source for all parts of the current study. A recent review of GeoSentinel Surveillance Network database, with a very large sample size was the basis for epidemiologic appraisals. https://www.ijtmgh.com/article_33292_0a38436397f65f4dba1b4393d81e9159.pdf