E.coli bacteria causing diarrhea, threatening travelers in the world, a narrative review

Document Type : Review Article


1 Department of Molecular Cell Biology and Genetics, Bushehr Branch, Islamic Azad University, Bushehr, Iran

2 3Supreme National Defense University

3 Department of Industrial Management, Mehr Alborz Higher Education Institute, Tehran, Iran



The most well-known gastrointestinal pathogen and typical component of the microbiota in the human gut is Escherichia coli.Enterotoxigenic,enteroinvasive,enteropathogenic,and enterohemorrhagic E.coli are some of the designated pathotypes that are used to categorize the many types of E. coli that cause diarrhea. Each pathotype's individual strains have a unique collection of virulence-related traits that influence the clinical, pathological, and epidemiological aspects of the illnesses they cause. In this succinct overview, we highlight the important characteristics that set the different pathotypes of diarrheagenic E. coli apart. The development of logical strategies for the management and prevention of E. coli-induced diarrhea has been facilitated by our growing understanding of the pathogenic processes of these bacteria. Investigations investigating the virulence of E. coli are also helping to provide light on the history and development of bacterial pathogens in general.
this species also contains primary pathogens that are responsible for a number of different diarrheal illness syndromes. There are presently five unique kinds of diarrheagenic E. coli that exhibit diverse virulence traits, interact with the intestinal mucosa in various ways,induce different clinical syndromes, have different epidemiologies,and belong to different O: H serotypes.
The most typical sickness among people who move from parts of the world with abundant resources to those with scarce resources is travelers' diarrhea. the anxiety of getting diarrhea Traveler's diarrhea (TD) episodes are almost always self-limiting and benign, but the dehydration that can exacerbate an episode can be severe and pose a greater health risk than the actual illness.