Document Type : Original Article
Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
Emergency department , Trauma Research Center , Baqiyatallah University of Medical Sciences, Tehran, Iran
School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran
Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran
Background: One of the recommended treatment methods for covid-19 is herbal treatments, which, if used, can be used as an effective preventive or supportive treatment in the treatment plan of patients with covid-19. PHR160 spray is combination of cineole, menthol, safran, safranal , crocin that each of these substances effects on respiratory diseases alone.
Aim: Investigating the effectiveness of PHR-160 spray, in the treatment of Covid-19.
Methods: The present study is a multicenter, double-blind, randomized clinical trial study, which was conducted in 4 medical centers. The study population includes all hospitalized patients with covid-19 who met the study inclusion criteria. The data collection tool was a checklist including: 1- demographic information, 2- vital signs, symptoms, CT scan changes, drug side effects (neural, cardiac and respiratory) at the beginning of admission and from the first to 10th day.
Result: There was no significant difference between the intervention and control groups in the study of demographic variables, vital signs, symptoms, CT scan changes, and drug side effects before using PHR-160 spray (P>0.05). Also, after using PHR-160 spray for ten days, there was no significant difference in in the admission to the intensive care unit, and patient mortality in the two groups (P>0.05)
Conclusion: Based on the results , PHR-160 spray has no beneficial effects in controlling the symptoms of patients with covid-19 and cannot play a effective role in improving the patient's condition and reducing the complications caused by the disease.
Keywords: PHR-160 spray , Covid-19 , treatment , patient.