Impact of Severe COVID-19 on Liver Health During Pregnancy: A Case Report on Subcapsular Liver Hematoma

Sahebdel, Behrokh; Golshahi, Fatemeh; Shirazi, Mahboobeh; Shirali, Elham; Saedi, Nafiseh; Nazemi, Pershang; Omrani, Mohammad Amin; Rahimi, Shima

doi:10.30491/ijtmgh.2024.472511.1425

Impact of Severe COVID-19 on Liver Health During Pregnancy: A Case Report on Subcapsular Liver Hematoma

Document Type : Case Report

Authors

Behrokh Sahebdel ¹

Fatemeh Golshahi ¹

Mahboobeh Shirazi ¹

Elham Shirali ¹

Nafiseh Saedi ¹

Pershang Nazemi ²

Mohammad Amin Omrani ³

Shima Rahimi ⁴

¹ Department of Obstetrics and Gynecology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran

² Department of Infectious diseases, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran

³ Student Research Committee, Faculty of medicine, Tehran University of Medical Sciences, Tehran, Iran.

⁴ Department of Obstetrics and Gynecology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

10.30491/ijtmgh.2024.472511.1425

Abstract

Subcapsular liver hematoma (SLH) is a rare and life-threatening condition that can complicate pregnancies, particularly in association with hypertensive disorders like preeclampsia. The incidence of SLH with rupture during pregnancy is extremely low, ranging from 1 in 40,000 to 1 in 250,000, but it carries a high maternal mortality rate. The exact pathogenesis remains unclear, though it is believed to involve endothelial dysfunction and inappropriate activation of the coagulation cascade. This case report presents a preeclamptic pregnant patient with severe respiratory distress due to SARS-CoV-2 and a rare complication of subcapsular liver hematoma. The patient underwent emergency surgery, but despite prompt intervention, the outcome was unfavorable. This case highlights the need for early diagnosis and a multidisciplinary approach in managing such high-risk pregnancies.

Keywords

SARS-CoV-2

infectious pandemic

hemorrhage

pregnancy

preeclampsia