The present study was conducted with the aim of investigating CFT compassion therapy on the quality of life, work and psychological empowerment of employees of textile factories in Borujerd. The research method was semi-experimental with a pre-test design with a control group. The statistical population included all the textile workers of Borujerd city in 1402, who were included in the study through the available sampling method, 30 people were included in the study and they were randomly divided into two groups of 15 people, the test and the control. The measurement tools in this research were World Health Organization's quality of life questionnaire (1998) and Spritzer's psychological empowerment (1995). The experimental group received ten, 75-minute sessions of compassion therapy, and the control group did not receive any intervention. Statistical data analysis was done using univariate covariance analysis and SPSS software. The significance level of the tests was P<0.05. The results of data analysis showed that after the intervention, the effect of compassion therapy on quality of life and psychological empowerment was significant (P<0.01). Based on the results of the research, it can be said that compassion therapy is a suitable intervention method for increasing the quality of life and psychological empowerment of textile factory employees. Therefore, using this treatment method alone or in combination with other intervention programs can increase the quality of life and Psychological empowerment of textile workers.