Pistacia atlantica as an Alternative Source for Anti-Inflammatory Drugs

Mirzaei Nodooshan, Majid

doi:10.30491/ijtmgh.2025.525729.1487

Pistacia atlantica as an Alternative Source for Anti-Inflammatory Drugs

Document Type : Policy Briefs

Author

Majid Mirzaei Nodooshan

Applied Virology Research Center, Biomedicine Technologies Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

10.30491/ijtmgh.2025.525729.1487

Abstract

Inflammation is a natural immune system response characterized by increased blood flow and vascular permeability. In this study, 50 mice were divided into 5 groups, and after inducing inflammation, the levels of inflammatory and anti-inflammatory cytokines, antioxidant enzymes, and oxidative stress were measured. The results showed that the gum extract of the Pistacia atlantica significantly reduced the levels of inflammatory cytokines and oxidative stress while increasing the levels of antioxidant enzymes and anti-inflammatory cytokines. Therefore, the gum extract of the Pistacia atlantica plant may be considered as a natural compound with anti-inflammatory properties for the treatment of immunological disorders caused by inflammation.

Keywords

Inflammation

Cytokines

Antioxidant enzymes

Oxidative stress

Pistacia atlantica