Preterm infants are exposed to multiple risks due to their early arrival in the world, which can have profound effects on their health and development, as well as on the mental health of their families. The NIDCAP program is designed as an observational approach and attention to the specific needs of premature infants, to facilitate the care and maintenance of these infants. This study examines the effects of NIDCAP in reducing stress and anxiety in families of premature infants. This narrative review shows that NIDCAP provides parents with a greater sense of control and comfort by creating a supportive and calm environment for infants and families. Also, the personalized care practices in this program help improve sleep quality and reduce stress in infants. Based on the review of available data, this article concludes that NIDCAP not only helps improve the clinical condition of premature infants, but also reduces the cognitive and emotional burden on families. Overall, NIDCAP can be considered an effective tool in the care of premature infants and increases psychological support for families. This study seeks to emphasize the importance of identifying and implementing such programs in health canters to help improve the quality of life of infants and their families.